Found 473 articles for: "atopic dermatitis"
Five-Year Trend in the Number of Dermatologic Clinical Drug Trials Registered on ClinicalTrials.gov
May 2015 | Volume 14 | Issue 5 | Original Article | 497 | Copyright © May 2015
BACKGROUND: There is a reported global decrease in the number of clinical trials conducted in recent years. We aimed to determine if this declining trend can be extrapolated to dermatologic clinical t...
Read MoreSteroid-Free Over-the-Counter Eczema Skin Care Formulations Reduce Risk of Flare, Prolong Time to Flare, and Reduce Eczema Symptoms in Pediatric Subjects With Atopic Dermatitis
May 2015 | Volume 14 | Issue 5 | Original Article | 478 | Copyright © May 2015
INTRODUCTION: Atopic dermatitis (AD) is a chronic skin condition associated with decreased barrier function resulting in periodic flare-ups of erythematous and pruritic lesions. Guidelines recommend d...
Read MoreThe Role of the Cutaneous Microbiome in Skin Cancer: Lessons Learned from the Gut
May 2015 | Volume 14 | Issue 5 | Original Article | 461 | Copyright © May 2015
The human microbiome has recently gained prominence as a major factor in health and disease. Here we review the literature regarding the microbiome and cancer and suggest how the microbiome may be man...
Read MorePipeline Previews
April 2015 | Volume 14 | Issue 4 | Features | 427 | Copyright © April 2015
Pipeline Previews brings to you information on the newest drugs and medical products as they become available to the dermatologic community. This department may include additional information from the...
Read MorePolypodium Leucotomos Extract: A Status Report on Clinical Efficacy and Safety
March 2015 | Volume 14 | Issue 3 | Original Article | 254 | Copyright © March 2015
Various extracts of polypodium leucotomos (PLE) applied topically or taken orally have been shown to have several beneficial antioxidant, photoprotectant, antimutagenic, and immunoregulatory effects. ...
Read MoreLeflunomide: An Immune Modulating Drug That May Have a Role in Controlling Secondary Infections With Review of Its Mechanisms of Action
March 2015 | Volume 14 | Issue 3 | Original Article | 230 | Copyright © March 2015
BACKGROUND: Leflunomide (LEF) is an immune modulator used most commonly for rheumatoid arthritis (RA). The mechanisms of action of LEF also include anti-microbial effects, particularly anti-viral effe...
Read MoreCost-Effectiveness Study of Pediatric Atopic Dermatitis in Asia: Atopiclair vs. Regular Emollient (AD-ATOP)
February 2015 | Volume 14 | Issue 2 | Original Article | 169 | Copyright © February 2015
BACKGROUND: Atopic dermatitis (AD) is a highly prevalent, chronic relapsing condition in childhood with significant financial burden and impact on the quality of life of patients and caregivers. Proac...
Read MoreThe Skin Microbiome: Is There a Role in the Pathogenesis of Atopic Dermatitis and Psoriasis?
February 2015 | Volume 14 | Issue 2 | Original Article | 127 | Copyright © February 2015
Skin microbiome studies have elucidated clinically pertinent information regarding its potential role in the pathogenesis of certain inflammatory skin disorders. Two of the most commonly diagnosed chr...
Read MoreMetastatic Hepatocellular Carcinoma With Paraneoplastic Itch: Effective Treatment With Naltrexone
December 2014 | Volume 13 | Issue 12 | Editorials | 1440 | Copyright © December 2014
Why do we Need Another Moisturizer for our Acne Patients?
August 2014 | Volume 13 | Issue 8 | Supplement Individual Articles | 88 | Copyright © August 2014
Transitioning From Brand to Generic With Topical Products and the Importance of Maintaining the Formulation and Therapeutic Profiles of the Original Product: Focus on Clocortolone Pivalate 0.1% Cream
July 2014 | Volume 13 | Issue 7 | Supplement Individual Articles | 77 | Copyright © July 2014
Topical corticosteroids (TCSs) are a major part of the foundation of treatment for a wide variety of eczematous and inflammatory skin disorders in both adults and children. Mid-potency TCSs represent ...
Read MoreNews, Views, and Reviews. Less May Be More for MRSA: The Latest on Antibiotics, the Utility of Packing an Abscess, and Decolonization Strategies
January 2014 | Volume 13 | Issue 1 | Features | 89 | Copyright © January 2014
The management of skin infections has evolved over time and new evidence suggests that less acute intervention may be as good or better. For acute treatment, evidence from the emergency medicine li...
Read MoreThe Phototoxic and Photoallergy Potential of Clindamycin Phosphate 1.2%/ Tretinoin 0.025% Gel for Facial Acne: Results of Two Single-Center, Evaluator-Blinded, Randomized, Vehicle-Controlled Phase 1 Studies in Healthy Volunteers
January 2014 | Volume 13 | Issue 1 | Original Article | 16 | Copyright © January 2014
BACKGROUND: A fixed-dose combination of clindamycin phosphate 1.2% and tretinoin 0.025% gel (VELTIN® (clindamycin phosphate and tretinoin) 1.2%/0.025% Gel [VELTIN]) (clindamycin/tretinoin gel) is cur...
Read MoreClinical Study Results of Desoximetasone Spray, 0.25% in Moderate to Severe Plaque Psoriasis
December 2013 | Volume 12 | Issue 12 | Original Article | 1404 | Copyright © December 2013
Two Phase 3, double-blind, randomized, vehicle-controlled parallel studies evaluated the efficacy and safety of desoximetasone spray 0.25%, a super-potent topical corticosteroid, twice daily vs vehicl...
Read MoreQuality of Life and Satisfaction of Patients After Full-Face Injections of Abobotulinum Toxin Type A: A Randomized, Phase IV Clinical Trial
December 2013 | Volume 12 | Issue 12 | Original Article | 1363 | Copyright © December 2013
BACKGROUND: Although botulinum toxin type A (BoNT-A) has been used effectively and safely to reduce facial dynamic wrinkles, few studies assessed patients' quality of life and satisfaction after trea...
Read MoreEvaluating and Treating the Adult Female Patient With Acne
December 2013 | Volume 12 | Issue 12 | Original Article | 1416 | Copyright © December 2013
Acne vulgaris is a common disease of the pilosebacous unit that affects an estimated 40-50 million Americans. Greater than 95% of teenage boys and between 83% and 85% of teenage girls suffer from acne...
Read MorePipeline Previews
November 2013 | Volume 12 | Issue 11 | Features | 1303 | Copyright © November 2013
Pipeline Previews brings to you information on the newest drugs and medical products as they become available to the dermatologic community. This department may include additional information from the...
Read MorePolymorphous Light Eruption Presenting as Pinhead Papular Eruption on the Face
November 2013 | Volume 12 | Issue 11 | Case Reports | 1285 | Copyright © November 2013
Polymorphic light eruption (PMLE) is the most common of the immunologically mediated photodermatoses.1 Onset is typically within the first three decades of life and affects females two to t...
Read MorePimecrolimus Cream and Tacrolimus Ointment in the Treatment of Atopic Dermatitis: A Pilot Study on Patient Preference
October 2013 | Volume 12 | Issue 10 | Original Article | 1145 | Copyright © October 2013
Background: Pimecrolimus cream 1% is approved for mild to moderate atopic dermatitis in children older than two years of age and adults. Tacrolimus ointment 0.03% is approved for moderate to severe at...
Read MoreNutritional Clinical Studies in Dermatology
October 2013 | Volume 12 | Issue 10 | Original Article | 1104 | Copyright © October 2013
BACKGROUND & AIMS: Nutrition has long been associated with skin health, beauty, integrity and aging through multiple pathways and cofactors implicated in skin biology. The onset and clinical course of...
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